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Medical · PET / SPECTNovel
Zr
40
89

Zirconium-89

A long-lived positron emitter (β⁺, 3.3 days) matched to the slow kinetics of monoclonal antibodies — the standard isotope for immuno-PET imaging.

3.3 daysPositron Emission (β⁺)
40 e⁻5 shells

Atomic Structure

40
Protons
49
Neutrons
K2 e⁻
L8 e⁻
M18 e⁻
N10 e⁻
O2 e⁻

Applications

  • Immuno-PET imaging
  • Antibody biodistribution tracking
  • Theranostic patient selection
  • Drug development trials

Production

Reaction
⁸⁹Y(p,n)⁸⁹Zr
Target
Yttrium-89
Source
16 MeV Cyclotron
16 MeV CyclotronYes
30 MeV CyclotronYes
70 MeV CyclotronYes
Nuclear ReactorNo

Threshold ~4 MeV, optimal 11–14 MeV.